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Literature summary for 3.1.1.3 extracted from

  • Kershaw, E.E.; Hamm, J.K.; Verhagen, L.A.; Peroni, O.; Katic, M.; Flier, J.S.
    Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin (2006), Diabetes, 55, 148-157.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.1.1.3

Activating Compound

Activating Compound Comment Organism Structure
additional information fasting induces the enzyme Mus musculus

Cloned(Commentary)

Cloned (Comment) Organism
overexpression of ATGL in 3T3-L1 cells via retroviral infection system, the cells show increased lipolysis Mus musculus

Protein Variants

Protein Variants Comment Organism
additional information knockdown of ATGL in 3T3-L1 cells by siRNA transfection, the cells show decreased lipolysis Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
additional information insulin suppresses expression of the enzyme Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus lipolysis is regulated by the opposing functions of the enzyme ATGL and adiponutrin, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Mus musculus Q8BJ56 male C75BL/6J mice
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Source Tissue

Source Tissue Comment Organism Textmining
3T3-L1 cell adipocytes, enzyme expression during differentiation of adipocytes, maximal at day 8, overview Mus musculus
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adipose tissue specific expression of ATGL Mus musculus
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additional information expression analysis of ATGL and adiponutrin Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information lipolysis is regulated by the opposing functions of the enzyme ATGL and adiponutrin, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
adipose triglyceride lipase
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 Mus musculus
ATGL
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 Mus musculus