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Literature summary for 3.1.1.29 extracted from

  • McFeeters, H.; Gilbert, M.J.; Thompson, R.M.; Setzer, W.N.; Cruz-Vera, L.R.; McFeeters, R.L.
    Inhibition of essential bacterial peptidyl-tRNA hydrolase activity by tropical plant extracts (2012), Nat. Prod. Commun., 7, 1107-1110.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
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Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Synonyms

Synonyms Comment Organism
peptidyl-tRNA hydrolase
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Escherichia coli
PTH
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Escherichia coli

General Information

General Information Comment Organism
malfunction since build-up of peptidyl-tRNAs is toxic, defects in enzyme function result in cell death Escherichia coli
physiological function the enzyme removes the peptide portion from peptidyl-tRNA, returning free tRNAs to participate in translation Escherichia coli