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Literature summary for 3.1.1.28 extracted from
- Specificity of two different purified acylcarnitine hydrolases from rat liver, their identity with other carboxylesterases, and their possible function (1985), Arch. Biochem. Biophys., 240, 801-810.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.093 | - |
Octanoyl-L-carnitine | low substrate concentration | Rattus norvegicus |  |
| 0.43 | - |
myristoyl-L-carnitine | - |
Rattus norvegicus | |
| 0.82 | - |
Decanoyl-L-carnitine | low substrate concentration | Rattus norvegicus | |
| 0.95 | - |
lauroyl-L-carnitine | - |
Rattus norvegicus | |
| 1.05 | - |
Decanoyl-L-carnitine | high substrate concentration | Rattus norvegicus | |
| 1.89 | - |
Octanoyl-L-carnitine | high substrate concentration | Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| palmitoyl carnitine + H2O | Rattus norvegicus | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
two enzyme forms | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1,3-diacylglycerides + H2O | faster than corresponding 1-monoglycerides | Rattus norvegicus | ? | - |
? | |
| 1,3-dioctanoylglycerol + H2O | - |
Rattus norvegicus | ? | - |
? | |
| decanoyl-L-carnitine + H2O | - |
Rattus norvegicus | decanoate + L-carnitine | - |
? | |
| lauroyl-L-carnitine + H2O | - |
Rattus norvegicus | lauric acid + L-carnitine | - |
? | |
| additional information | not: p-nitrophenyl palmitate, glycerol tripalmitate, cholesterol palmitate | Rattus norvegicus | ? | - |
? | |
| additional information | not: acetylcarnitine, butyrylthiocholine | Rattus norvegicus | ? | - |
? | |
| myristoyl-L-carnitine + H2O | - |
Rattus norvegicus | myristic acid + L-carnitine | - |
? | |
| octanoyl-L-carnitine + H2O | - |
Rattus norvegicus | octanoate + L-carnitine | - |
? | |
| palmitoyl carnitine + H2O | - |
Rattus norvegicus | ? | - |
? | |
| palmitoyl-L-carnitine + H2O | - |
Rattus norvegicus | palmitic acid + L-carnitine | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 10 | - |
Rattus norvegicus |
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