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BRENDA support

Literature summary for 3.1.1.2 extracted from

  • Popa, C.; van Tits, L.J.; Barrera, P.; Lemmers, H.L.; van den Hoogen, F.H.; van Riel, P.L.; Radstake, T.R.; Netea, M.G.; Roest, M.; Stalenhoef, A.F.
    Anti-inflammatory therapy with tumour necrosis factor alpha inhibitors improves high-density lipoprotein cholesterol antioxidative capacity in rheumatoid arthritis patients (2009), Ann. Rheum. Dis., 68, 868-872.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information after anti-tumour necrosis factor therapy, arylesterase significantly increases after 2 weeks from the first infusion and also remains high after 6 months Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phenyl acetate + H2O
-
Homo sapiens phenol + acetate
-
?

Synonyms

Synonyms Comment Organism
ARE
-
Homo sapiens
arylesterase
-
Homo sapiens

General Information

General Information Comment Organism
physiological function after 6 months of anti-tumour necrosis factor therapy, initial improvement of arylesterase activity parallels a decrease in the inflammatory status Homo sapiens