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Literature summary for 3.1.1.2 extracted from
- Paraoxonase 1 (PON1) attenuates diabetes development in mice through its antioxidative properties (2008), Free Radic. Biol. Med., 44, 1951-1959.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | PON1 overexpression is associated with decreased diabetes-induced macrophage oxidative stress, decreased diabetes development, and decreased mortality | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P52430 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| J774A.1 cell | - |
Mus musculus | - |
| macrophage | - |
Mus musculus | - |
| serum | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | PON1 is a lipo-lactonase which is associated with high density lipoprotein and possesses antioxidative properties | Mus musculus | ? | - |
? |  |
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Release 2023.1 (January 2023)
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