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Literature summary for 3.1.1.2 extracted from

  • Khersonsky, O.; Tawfik, D.S.
    Structure-reactivity studies of serum paraoxonase PON1 suggest that its native activity is lactonase (2005), Biochemistry, 44, 6371-6382.
    View publication on PubMed
Search for more literature for 3.1.1.2

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1
-
 4-chlorophenyl acetate
-
 Homo sapiens
1.19
-
 2,3-difluorophenyl acetate
-
 Homo sapiens
1.2
-
 phenyl acetate
-
 Homo sapiens
1.26
-
 p-tolyl acetate
-
 Homo sapiens
1.4
-
 3-fluorophenyl acetate
-
 Homo sapiens
1.5
-
 4-nitrophenyl acetate
-
 Homo sapiens
1.5
-
 2-fluorophenyl acetate
-
 Homo sapiens
1.9
-
 3-cyanophenyl acetate
-
 Homo sapiens
2
-
 4-acetoxy methyl benzoate
-
 Homo sapiens
2
-
 2,6-difluorophenyl acetate
-
 Homo sapiens
2.1
-
 3,4-dimethyl phenyl acetate
-
 Homo sapiens
2.2
-
 3-nitrophenyl acetate
-
 Homo sapiens
2.23
-
 2,4-difluorophenyl acetate
-
 Homo sapiens
2.3
-
 4-acetoxybenzaldehyde
-
 Homo sapiens
2.6
-
 4-acetoxyacetophenone
-
 Homo sapiens
4.1
-
 4-methoxy phenyl acetate
-
 Homo sapiens
5
-
 Benzyl acetate
-
 Homo sapiens
5
-
 1-phenylvinyl acetate
-
 Homo sapiens
10
-
 butyl acetate
-
 Homo sapiens
13
-
 propyl acetate
-
 Homo sapiens
15.4
-
 ethyl acetate
-
 Homo sapiens
19
-
 2,2,2-trifluoroethyl acetate
-
 Homo sapiens
24.8
-
 2,2-difluoroethyl acetate
-
 Homo sapiens
54
-
 2-fluoroethyl acetate
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P27169
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-phenylvinyl acetate + H2O
-
 Homo sapiens 1-phenylethylenol + acetate
-
 ?
2,2,2-trifluoroethyl acetate + H2O
-
 Homo sapiens 2,2,2-trifluoroethanol + acetate
-
 ?
2,2-difluoroethyl acetate + H2O
-
 Homo sapiens 2,2-difluoroethanol + acetate
-
 ?
2,3-difluorophenyl acetate + H2O
-
 Homo sapiens 2,3-difluorophenol + acetate
-
 ?
2,4-difluorophenyl acetate + H2O
-
 Homo sapiens 2,4-difluorophenol + acetate
-
 ?
2,6-difluorophenyl acetate + H2O
-
 Homo sapiens 2,6-difluorophenol + acetate
-
 ?
2-fluoroethyl acetate + H2O
-
 Homo sapiens 2-fluoroethanol + acetate
-
 ?
2-fluorophenyl acetate + H2O
-
 Homo sapiens 2-fluorophenol + acetate
-
 ?
3,4-dimethyl phenyl acetate + H2O
-
 Homo sapiens 3,4-dimethylphenol + acetate
-
 ?
3-cyanophenyl acetate + H2O
-
 Homo sapiens 3-cyanophenol + acetate
-
 ?
3-fluorophenyl acetate + H2O
-
 Homo sapiens 3-fluorophenol + acetate
-
 ?
3-nitrophenyl acetate + H2O
-
 Homo sapiens 3-nitrophenol + acetate
-
 ?
4-acetoxyacetophenone + H2O
-
 Homo sapiens 4-hydroxyacetophenone + acetate
-
 ?
4-acetoxybenzaldehyde + H2O
-
 Homo sapiens 4-hydroxybenzaldehyde + acetate
-
 ?
4-chlorophenyl acetate + H2O
-
 Homo sapiens 4-chlorophenol + acetate
-
 ?
4-cyanophenyl acetate + H2O
-
 Homo sapiens 4-cyanophenol + acetate
-
 ?
4-diethyl phosphate methyl benzoate + H2O
-
 Homo sapiens ?
-
 ?
4-methoxy phenyl acetate + H2O
-
 Homo sapiens 4-methoxy phenol + acetate
-
 ?
4-methylphenyl acetate + H2O
-
 Homo sapiens 4-methylphenol + acetate
-
 ?
4-nitrophenyl acetate + H2O
-
 Homo sapiens 4-nitrophenol + acetate
-
 ?
benzyl acetate + H2O
-
 Homo sapiens benzyl alcohol + acetate
-
 ?
butyl acetate + H2O
-
 Homo sapiens butanol + acetate
-
 ?
ethyl acetate + H2O
-
 Homo sapiens ethanol + acetate
-
 ?
isopropyl acetate + H2O
-
 Homo sapiens isobutanol + acetate
-
 ?
methyl 4-(acetyloxy)benzoate + H2O
-
 Homo sapiens methyl 4-hydroxybenzoate + acetate
-
 ?
phenyl acetate + H2O
-
 Homo sapiens phenol + acetate
-
 ?
propyl acetate + H2O
-
 Homo sapiens propanol + acetate
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.0008
-
 Benzyl acetate
-
 Homo sapiens
0.02
-
 Benzyl acetate pH 8.0 Homo sapiens
0.242
-
 ethyl acetate
-
 Homo sapiens
0.244
-
 4-diethyl phosphate methyl benzoate pH 8.0 Homo sapiens
0.27
-
 butyl acetate
-
 Homo sapiens
0.4
-
 propyl acetate
-
 Homo sapiens
0.5
-
 2-fluoroethyl acetate
-
 Homo sapiens
0.82
-
 2,2-difluoroethyl acetate
-
 Homo sapiens
1
-
 1-phenylvinyl acetate
-
 Homo sapiens
4
-
 2,2,2-trifluoroethyl acetate
-
 Homo sapiens
13
-
 4-acetoxyacetophenone pH 8.0 Homo sapiens
14
-
 4-acetoxy methyl benzoate
-
 Homo sapiens
23
-
 4-cyanophenyl acetate
-
 Homo sapiens
26
-
 4-nitrophenyl acetate
-
 Homo sapiens
26
-
 4-acetoxybenzaldehyde
-
 Homo sapiens
51
-
 3,4-dimethyl phenyl acetate
-
 Homo sapiens
59
-
 3-nitrophenyl acetate
-
 Homo sapiens
68
-
 p-tolyl acetate
-
 Homo sapiens
117
-
 4-chlorophenyl acetate
-
 Homo sapiens
125
-
 3-cyanophenyl acetate
-
 Homo sapiens
145
-
 2,6-difluorophenyl acetate
-
 Homo sapiens
334
-
 2,4-difluorophenyl acetate
-
 Homo sapiens
403
-
 2,3-difluorophenyl acetate
-
 Homo sapiens
431
-
 2-fluorophenyl acetate
-
 Homo sapiens
571
-
 3-fluorophenyl acetate
-
 Homo sapiens
698
-
 phenyl acetate
-
 Homo sapiens