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Literature summary for 3.1.1.2 extracted from
- Cloning, high level expression of human paraoxonase-3 in Sf9 cells and pharmacological characterization of its product (2005), Biochem. Pharmacol., 70, 1019-1025.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression of PON3 in Spodoptera frugiperda Sf9 cells using the baculovirus expression system | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| EDTA | 0.005-0.01 mM | Homo sapiens |  |
| PMSF | 1 mM | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 7.46 | - |
phenyl acetate | pH 8.0, 37°C | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | Q15166 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme can delay and inhibit low-density lipoprotein oxidation in a dose-dependent manner | Homo sapiens | ? | - |
? | |
| phenyl acetate + H2O | - |
Homo sapiens | phenol + acetate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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