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Literature summary for 3.1.1.13 extracted from

  • Langston, T.B.; Hylemon, P.B.; Grogan, W.M.
    Over-expression of hepatic neutral cytosolic cholesteryl ester hydrolase in mice increases free cholesterol and reduces expression of HMG-CoAR, CYP27, and CYP7A1 (2005), Lipids, 40, 31-38.
    View publication on PubMed

Application

Application Comment Organism
medicine enzyme overexpression results in elevation of free cholesterol and depletion of cholesteryl esters, which are resistant to compensatory responses by other enzymes of cholesterol homeostasis Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
over-expression in mice
-

Source Tissue

Source Tissue Comment Organism Textmining