Literature summary for 3.1.1.118 extracted from

Yamashita, A.; Kumazawa, T.; Koga, H.; Suzuki, N.; Oka, S.; Sugiura, T.
Generation of lysophosphatidylinositol by DDHD domain containing 1 (DDHD1) Possible involvement of phospholipase D/phosphatidic acid in the activation of DDHD1 (2010), Biochim. Biophys. Acta, 1801, 711-720 .

Search for more literature for 3.1.1.118

Activating Compound

Activating Compound	Comment	Organism	Structure
ionomycin	-	Homo sapiens
lysophosphatidic acid	weak activation	Homo sapiens
lysophosphatidylinositol	weak activation	Homo sapiens
additional information	not activated by phosphatidylethanolamine, phosphatidylcholine and free fatty acid	Homo sapiens
phosphatidic acid	-	Homo sapiens
phosphatidylserine	-	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in HEK-293 cells	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
n-butanol	-	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q8NEL9	-	-

Purification (Commentary)

Purification (Comment)	Organism
anti-FLAG-M2 agarose column chromatography	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
1-stearoyl-2-arachidonoyl-phosphatidylinositol + H2O	-	Homo sapiens	2-arachidonoyl-lysophosphatidylinositol + stearate	-	?

Subunits

Subunits	Comment	Organism
?	x * 120000, FLAG-tagged enzyme, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
DDHD domain-containing protein 1	-	Homo sapiens
DDHD1	-	Homo sapiens
PA-PLA1	-	Homo sapiens
phosphatidic acid-preferring phospholipase A1	-	Homo sapiens

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Release 2023.1 (January 2023)