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Literature summary for 3.1.1.110 extracted from

  • Cao, Y.; Xian, M.; Zou, H.; Zhang, H.
    Metabolic engineering of Escherichia coli for the production of xylonate (2013), PLoS ONE, 8, e67305 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis production of xylonate from xylose in Escerichia coli. Through the coexpression of a xylose dehydrogenase (XdH) and a xylonolactonase (XylC) from Caulobacter crescentus, the recombinant strain can convert 1 g/l xylose to 0.84 g/l xylonate and 0.10 g/l xylonolactone. After disruption of endogenous genes XylA and XylB encoding xylose isomerase and xylulose kinase, the finally engineered strain under fed-batch conditions, produces up to 27.3 g/l xylonate and 1.7 g/l xylonolactone from 30 g/l xylose, about 88% of the theoretical yield Caulobacter vibrioides

Organism

Organism UniProt Comment Textmining
Caulobacter vibrioides Q9A9Z1
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Caulobacter vibrioides ATCC 19089 Q9A9Z1
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Synonyms

Synonyms Comment Organism
CC_0820
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Caulobacter vibrioides
XylC
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Caulobacter vibrioides