Literature summary for 3.1.1.1 extracted from

Zhuang, X.M.; Wei, X.; Tan, Y.; Xiao, W.B.; Yang, H.Y.; Xie, J.W.; Lu, C.; Li, H.
Contribution of carboxylesterase and cytochrome P450 to the bioactivation and detoxification of isocarbophos and its enantiomers in human liver microsomes (2014), Toxicol. Sci., 140, 40-48.

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Inhibitors

Inhibitors	Comment	Organism	Structure
bis(4-nitrophenyl) phosphoric acid	97% inhibition at 1 mM	Homo sapiens
EGTA	minimal inhibition	Homo sapiens
tetraisopropyl diphosphoramide	67% inhibition at 0.5 mM	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
microsome	-	Homo sapiens	-	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
isocarbophos + H2O	-	Homo sapiens	?	-	?

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Release 2023.1 (January 2023)