Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.1.1.1 extracted from

  • Yang, D.; Pearce, R.E.; Wang, X.; Gaedigk, R.; Wan, Y.J.; Yan, B.
    Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin (2009), Biochem. Pharmacol., 77, 238-247.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
Homo sapiens
-
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl acetate + H2O
-
Homo sapiens 4-nitrophenol + acetate
-
?
aspirin + H2O
-
Homo sapiens acetate + salicylate
-
ir
deltamethrin + H2O
-
Homo sapiens 3-phenoxybenzaldehyde + (1R,3R)-3-(2,2-dibromoethenyl)-2,2-dimethylcyclopropanecarboxylate + cyanide
-
?
oseltamivir + H2O
-
Homo sapiens ?
-
?
permethrin + H2O the cis-form of permethrin is favorably hydrolyzed by isozyme HCE2, whereas the trans-form is comparably hydrolyzed by HCE1 and HCE2 Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
HCE1 isozyme Homo sapiens
HCE2 isozyme Homo sapiens