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Literature summary for 2.8.3.5 extracted from

  • Cong, W.; Ma, W.; Zhao, T.; Zhu, Z.; Wang, Y.; Tan, Y.; Li, X.; Jin, L.; Cai, L.
    Metallothionein prevents diabetes-induced cardiac pathological changes, likely via the inhibition of succinyl-CoA:3-ketoacid coenzyme A transferase-1 nitration at Trp(374) (2013), Am. J. Physiol. Endocrinol. Metab., 304, E826-E835.
    View publication on PubMed
Search for more literature for 2.8.3.5

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58000
-
 x * 58000, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q9D0K2
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
nitrosylation diabetes is associated with a higher nitrosylation degree of tyrosine 76 and tyrosine374 Mus musculus

Source Tissue

Source Tissue Comment Organism Textmining
heart
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
succinyl-CoA + acetoacetate
-
 Mus musculus succinate + acetoacetyl-CoA
-
 ?

Subunits

Subunits Comment Organism
? x * 58000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
SCOT
-
 Mus musculus
succinyl-CoA:3-ketoacid coenzyme A transferase-1
-
 Mus musculus

Expression

Organism Comment Expression
Mus musculus the enzyme catalytic activity is significantly reduced in the hearts of diabetic wild type diabetic mice at weeks 4-12 postinduction, with the lowest level observed at week 4 postinduction down