BRENDA - Enzyme Database
show all sequences of 2.8.3.16

Lactobacillus gasseri Gasser AM63T degrades oxalate in a multistage continuous culture simulator of the human colonic microbiota

Lewanika, T.R.; Reid, S.J.; Abratt, V.R.; MacFarlane, G.T.; MacFarlane, S.; FEMS Microbiol. Ecol. 61, 110-120 (2007)

Data extracted from this reference:

Application
Application
Commentary
Organism
medicine
potential therapeutic use in managing oxalate kidney stone disease in humans
Lactobacillus gasseri
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
formyl-CoA + oxalate
Lactobacillus gasseri
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
formate + oxalyl-CoA
-
-
r
formyl-CoA + oxalate
Lactobacillus gasseri Gasser AM63T
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
formate + oxalyl-CoA
-
-
r
Organism
Organism
UniProt
Commentary
Textmining
Lactobacillus gasseri
A0A087QB11
Gasser AM63T
-
Lactobacillus gasseri Gasser AM63T
A0A087QB11
Gasser AM63T
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
Substrate Product ID
formyl-CoA + oxalate
-
692373
Lactobacillus gasseri
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
692373
Lactobacillus gasseri
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
-
692373
Lactobacillus gasseri Gasser AM63T
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
692373
Lactobacillus gasseri Gasser AM63T
formate + oxalyl-CoA
-
-
-
r
Synonyms
Synonyms
Commentary
Organism
formyl coenzyme A transferase
-
Lactobacillus gasseri
FRC
-
Lactobacillus gasseri
Application (protein specific)
Application
Commentary
Organism
medicine
potential therapeutic use in managing oxalate kidney stone disease in humans
Lactobacillus gasseri
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
ID
formyl-CoA + oxalate
Lactobacillus gasseri
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
formate + oxalyl-CoA
-
-
r
formyl-CoA + oxalate
Lactobacillus gasseri Gasser AM63T
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
formate + oxalyl-CoA
-
-
r
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
ID
formyl-CoA + oxalate
-
692373
Lactobacillus gasseri
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
692373
Lactobacillus gasseri
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
-
692373
Lactobacillus gasseri Gasser AM63T
formate + oxalyl-CoA
-
-
-
r
formyl-CoA + oxalate
colonic oxalate-degrading bacteria have been shown to play an important role in human kidney stone formation
692373
Lactobacillus gasseri Gasser AM63T
formate + oxalyl-CoA
-
-
-
r
Other publictions for EC 2.8.3.16
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
739759
Herve
Diversity and ecology of oxalo ...
Actinobacteria, Firmicutes, Proteobacteria
World J. Microbiol. Biotechnol.
32
28
2016
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3
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8
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3
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6
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3
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-
-
3
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-
-
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-
-
-
-
-
-
-
-
-
-
726452
Mullins
Formyl-coenzyme A (CoA):oxalat ...
Acetobacter aceti 1023, Acetobacter aceti
Protein Sci.
21
686-696
2012
-
-
1
1
-
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-
2
1
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4
2
-
4
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1
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2
1
3
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2
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1
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1
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2
1
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4
2
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1
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2
1
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-
2
-
-
-
-
1
-
-
1
2
2
692851
Toyota
Differential substrate specifi ...
Escherichia coli, Escherichia coli MG1655, Oxalobacter formigenes
J. Bacteriol.
190
2556-2564
2008
-
-
2
1
2
-
4
10
-
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3
-
32
-
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2
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6
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4
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2
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2
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1
2
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4
2
10
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3
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2
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6
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-
693216
Berthold
Reinvestigation of the catalyt ...
Oxalobacter formigenes
J. Biol. Chem.
283
6519-6529
2008
-
-
1
1
3
-
2
8
-
-
-
1
-
2
-
-
1
-
-
-
-
1
2
1
1
-
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2
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1
-
1
3
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2
2
8
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1
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1
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1
2
1
-
-
-
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-
-
-
-
-
-
-
-
-
693608
Khammar
Use of the frc gene as a molec ...
Ancylobacter oerskovii, Ancylobacter polymorphus, Arquibacter sp., Azorhizobium sp., Azospirillum brasilense, Azospirillum lipoferum, Bradyrhizobium japonicum, Bradyrhizobium sp., Cupriavidus necator, Cupriavidus necator JMP 134-1, Cupriavidus oxalaticus, Escherichia coli, Herminiimonas arsenicoxydans, Herminiimonas saxobsidens, Janthinobacterium sp. Marseille, Methylobacterium organophilum, Methylorubrum extorquens, Methylorubrum thiocyanatum, Oxalicibacterium flavum, Oxalobacter formigenes, Pandoraea sp., Paraburkholderia xenovorans, Rhodopseudomonas palustris, Shigella flexneri, Starkeya novella, Streptomyces avermitilis, Streptomyces coelicolor, Streptomyces violaceoruber, Variovorax paradoxus, Xanthobacter autotrophicus, Xanthobacter flavus, Xanthomonas sp.
J. Microbiol. Methods
76
120-127
2008
-
93
31
-
-
-
-
-
-
-
-
36
-
39
-
-
-
-
-
62
-
-
72
-
35
-
-
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-
-
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-
-
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-
-
-
105
35
-
-
-
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-
-
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-
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-
36
-
-
-
-
-
70
-
-
72
-
-
-
-
-
-
-
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-
-
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-
-
-
-
674225
Turroni
Oxalate consumption by lactoba ...
Lactobacillus acidophilus
J. Appl. Microbiol.
103
1600-1609
2007
-
-
1
-
-
-
-
-
-
-
1
1
-
5
-
-
-
-
-
-
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-
2
1
-
1
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-
-
1
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1
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-
-
-
-
-
-
-
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-
1
1
-
-
-
-
-
-
-
-
2
1
1
-
-
-
1
-
-
-
-
-
-
-
-
-
692373
Lewanika
Lactobacillus gasseri Gasser A ...
Lactobacillus gasseri, Lactobacillus gasseri Gasser AM63T
FEMS Microbiol. Ecol.
61
110-120
2007
-
1
-
-
-
-
-
-
-
-
-
2
-
6
-
-
-
-
-
-
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4
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2
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1
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2
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4
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-
692677
Ye
Stable expression of the oxc a ...
Oxalobacter formigenes
Int. J. Mol. Med.
20
521-526
2007
-
1
1
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1
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1
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4
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2
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2
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1
1
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1
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1
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-
2
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-
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-
-
-
671452
Azcarate-Peril
Transcriptional and functional ...
Bifidobacterium animalis subsp. lactis, Lactobacillus acidophilus, Lactobacillus acidophilus NCFM, Lactobacillus gasseri
Appl. Environ. Microbiol.
72
1891-1899
2006
1
-
3
-
1
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-
-
-
-
-
2
-
14
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4
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1
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3
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1
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2
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4
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662253
Jonsson
Kinetic and mechanistic charac ...
Oxalobacter formigenes
J. Biol. Chem.
279
36003-36012
2004
-
-
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1
3
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2
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1
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3
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1
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1
1
1
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2
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1
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-
1
3
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2
1
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1
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1
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-
-
-
1
1
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-
-
2
-
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-
645962
Ricagno
Crystallization and preliminar ...
Oxalobacter formigenes
Acta Crystallogr. Sect. D
59
1276-1277
2003
-
-
-
1
-
-
-
-
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1
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3
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1
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1
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1
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1
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1
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1
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-
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-
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-
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645963
Ricagno
Formyl-CoA transferase enclose ...
Oxalobacter formigenes
EMBO J.
22
3210-3219
2003
-
-
1
1
-
-
-
-
-
-
-
1
-
4
-
-
1
1
-
3
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4
1
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-
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1
-
1
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-
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1
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1
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3
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4
1
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-
645961
Sidhu
DNA sequencing and expression ...
Oxalobacter formigenes
J. Bacteriol.
179
3378-3381
1997
-
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1
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-
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-
-
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1
1
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4
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1
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3
1
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1
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1
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1
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3
1
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-
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-
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-
-
-
645960
Baetz
-
Localization of oxalyl-coenzym ...
Oxalobacter formigenes, Oxalobacter formigenes OxB / ATCC 35274
Syst. Appl. Microbiol.
15
167-171
1992
-
-
-
-
-
-
-
-
1
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2
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2
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1
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1
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1
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2
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-
645959
Baetz
Purification and characterizat ...
Oxalobacter formigenes
J. Bacteriol.
172
3537-3540
1990
-
-
-
-
-
-
2
3
-
-
2
1
-
2
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1
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1
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3
1
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1
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1
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1
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2
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2
1
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1
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1
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3
1
1
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1
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1
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