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Literature summary for 2.8.3.15 extracted from

  • Leutwein, C.; Heider, J.
    Anaerobic toluene-catabolic pathway in denitrifying Thauera aromatica: activation and beta-oxidation of the first intermediate, (R)-(+)-benzylsuccinate (1999), Microbiology, 145, 3265-3271.
    View publication on PubMed
Search for more literature for 2.8.3.15

General Stability

General Stability Organism
stable against oxygen Thauera aromatica

Localization

Localization Comment Organism GeneOntology No. Textmining
soluble
-
 Thauera aromatica
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Thauera aromatica involved in anaerobic catabolism of toluene and is a strictly toluene-induced enzyme that catalyses the reversible regio- and enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA ?
-
 ?
succinyl-CoA + (R)-2-benzylsuccinate Thauera aromatica
-
 succinate + (R)-2-benzylsuccinyl-CoA
-
 ?

Organism

Organism UniProt Comment Textmining
Thauera aromatica
-
 denitrifying bacterium
-

Reaction

Reaction Comment Organism Reaction ID
succinyl-CoA + (R)-2-benzylsuccinate = succinate + (R)-2-benzylsuccinyl-CoA mechanism via radical intermediates Thauera aromatica
a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
15
-
-
 Thauera aromatica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information absolutely specific for (R)-(+)-benzylsuccinate Thauera aromatica ?
-
 ?
additional information involved in anaerobic catabolism of toluene and is a strictly toluene-induced enzyme that catalyses the reversible regio- and enantio-selective synthesis of (R)-2-benzylsuccinyl-CoA Thauera aromatica ?
-
 ?
succinyl-CoA + (R)-2-benzylsuccinate
-
 Thauera aromatica succinate + (R)-2-benzylsuccinyl-CoA
-
 ?
succinyl-CoA + (R)-2-benzylsuccinate
-
 Thauera aromatica succinate + (R)-2-benzylsuccinyl-CoA
-
 r