Literature summary for 2.8.2.8 extracted from

Pan, Y.; Woodbury, A.; Esko, J.D.; Grobe, K.; Zhang, X.
Heparan sulfate biosynthetic gene Ndst1 is required for FGF signaling in early lens development (2006), Development, 133, 4933-4944.

Search for more literature for 2.8.2.8

Protein Variants

Protein Variants	Comment	Organism
additional information	early lens defects occur in Ndst1-knockout embryos, molecular defects underlying lens induction in Ndst1 mutants and phenotype, overview, Ndst1 knockout does not affect canonical bone morphogenic protein and Wnt signaling in the lens	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	C57BL/6 mice, gene Ndst1	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
eye	-	Mus musculus	-
lens	gene Ndst1 is expressed during lens development, in lens epithelium, strong expression occurs in both the lens placode and in the optic vesicle in mouse embryos at stage E9.5, overview	Mus musculus	-
retina	-	Mus musculus	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)