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Literature summary for 2.8.2.8 extracted from

  • Orellana, A.; Hirschberg, C.B.; Wei, Z.; Swiedler, S.J.; Ishihara, M.
    Molecular cloning and expression of a glycosaminoglycan N-acetylglucosaminyl N-deacetylase/N-sulfotransferase from a heparin-producing cell line (1994), J. Biol. Chem., 269, 2270-2276.
    View publication on PubMed
Search for more literature for 2.8.2.8

Cloned(Commentary)

Cloned (Comment) Organism
-
 Mus musculus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0009
-
 N-deacetylase K5-polysaccharide
-
 Mus musculus
0.0224
-
 N-deacetylase K5-polysaccharide
-
 Mus musculus
0.0407
-
 3'-phosphoadenylylsulfate with N-deacetylase K5-polysaccharide Mus musculus
0.108
-
 3'-phosphoadenylylsulfate with N-deacetylase K5-polysaccharide Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine Mus musculus may be involved in biosynthesis of heparin and not of heparan sulfate adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
mastocytoma cell ie. MST cell Mus musculus
-
MST cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + N-deacetylase K5-polysaccharide
-
 Mus musculus ?
-
 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine substrate needs to be deacetylated Mus musculus adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine may be involved in biosynthesis of heparin and not of heparan sulfate Mus musculus adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine
-
 ?
3'-phosphoadenylylsulfate + heparan sulfate
-
 Mus musculus adenosine 3',5'-bisphosphate + N-sulfoheparan sulfate
-
 ?
3'-phosphoadenylylsulfate + N-deacetylated K5-polysaccharide from E. coli K5-derived capsular polysaccharide Mus musculus ?
-
 ?