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Literature summary for 2.8.2.4 extracted from

  • Uno, Y.; Murayama, N.; Yamazaki, H.
    Molecular and functional characterization of cytosolic sulfotransferases in cynomolgus macaque (2019), Biochem. Pharmacol., 166, 153-162 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
gene SULT1E1, DNA and amino acid sequence determination and analysis, localized on chromosome 5, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis Macaca fascicularis

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Macaca fascicularis 5829
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 1-naphthol Macaca fascicularis best substrate adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
?
3'-phosphoadenylyl sulfate + 17beta-estradiol Macaca fascicularis
-
adenosine 3',5'-bisphosphate + 17beta-estradiol sulfate
-
?
3'-phosphoadenylyl sulfate + 4-nitrophenol Macaca fascicularis
-
adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone Macaca fascicularis
-
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
?
3'-phosphoadenylyl sulfate + dopamine Macaca fascicularis
-
adenosine 3',5'-bisphosphate + dopamine sulfate
-
?
3'-phosphoadenylyl sulfate + estrone Macaca fascicularis
-
adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?

Organism

Organism UniProt Comment Textmining
Macaca fascicularis Q2XV97
-
-

Source Tissue

Source Tissue Comment Organism Textmining
jejunum predominantly Macaca fascicularis
-
additional information quantitative real-time RT-PCR enzyme expression analysis in female and male tissue samples, tissue distribution and expression pattern, overview Macaca fascicularis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 1-naphthol
-
Macaca fascicularis adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
?
3'-phosphoadenylyl sulfate + 1-naphthol best substrate Macaca fascicularis adenosine 3',5'-bisphosphate + 1-naphthyl sulfate
-
?
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
Macaca fascicularis adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
?
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
Macaca fascicularis adenosine 3',5'-bisphosphate + 17beta-estradiol sulfate
-
?
3'-phosphoadenylyl sulfate + 4-nitrophenol
-
Macaca fascicularis adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone
-
Macaca fascicularis adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
?
3'-phosphoadenylyl sulfate + dehydroepiandrosterone best substrate Macaca fascicularis adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
?
3'-phosphoadenylyl sulfate + dopamine
-
Macaca fascicularis adenosine 3',5'-bisphosphate + dopamine sulfate
-
?
3'-phosphoadenylyl sulfate + estrone
-
Macaca fascicularis adenosine 3',5'-bisphosphate + estrone 3-sulfate
-
?

Synonyms

Synonyms Comment Organism
cytosolic sulfotransferase
-
Macaca fascicularis
SULT1E1
-
Macaca fascicularis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Macaca fascicularis

General Information

General Information Comment Organism
evolution gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. SULT1B1 and SULT1E1 form a gene cluster Macaca fascicularis