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Literature summary for 2.8.2.4 extracted from

  • Xu, Y.; Yang, X.; Wang, Z.; Li, M.; Ning, Y.; Chen, S.; Yin, L.; Li, X.
    Estrogen sulfotransferase (SULT1E1) regulates inflammatory response and lipid metabolism of human endothelial cells via PPARgamma (2013), Mol. Cell. Endocrinol., 369, 140-149.
    View publication on PubMed
Search for more literature for 2.8.2.4

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
35000
-
 x * 35000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol Homo sapiens
-
 adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + estrogen Homo sapiens
-
 adenosine 3',5'-bisphosphate + estrogen 3-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Homo sapiens P49888
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
 Homo sapiens
-
primary cell
-
 Homo sapiens
-
umbilical vein endothelial cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + 17beta-estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylyl sulfate + estrogen
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrogen 3-sulfate
-
 ?
3'-phosphoadenylylsulfate + 17beta-estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + 17beta-estradiol sulfate
-
 ?
3'-phosphoadenylylsulfate + estrogen
-
 Homo sapiens adenosine 3',5'-bisphosphate + estrogen sulfate
-
 ?

Subunits

Subunits Comment Organism
? x * 35000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
estrogen sulfotransferase
-
 Homo sapiens
SULT1E1
-
 Homo sapiens

General Information

General Information Comment Organism
malfunction knock-down of the enzyme in HUVEC cells results in regulation of genes involved in inflammation and lipid metabolism Homo sapiens
metabolism estrogen sulfotransferase SULT1E1 regulates inflammatory response and lipid metabolism of human endothelial cells via proliferator-activated receptor gamma Homo sapiens
physiological function 17beta-estradiol sulfation catalyzed by SULT1E1 plays an important role in modulating endothelial cell function Homo sapiens