Literature summary for 2.8.2.4 extracted from

Bacallao, K.; Leon, L.; Gabler, F.; Soto, E.; Romero, C.; Valladares, L.; Vega, M.
In situ estrogen metabolism in proliferative endometria from untreated women with polycystic ovarian syndrome with and without endometrial hyperplasia (2008), J. Steroid Biochem. Mol. Biol., 110, 163-169.

Search for more literature for 2.8.2.4

Inhibitors

Inhibitors	Comment	Organism	Structure
chloroform	excess chloroform inactivates	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytosol	-	Homo sapiens	5829	-

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3'-phosphoadenylyl sulfate + estrone	Homo sapiens	-	adenosine 3',5'-bisphosphate + estrone 3-sulfate	-	?
additional information	Homo sapiens	the endocrinological status of women bearing polycystic ovarian syndrome, PCOS, affects the endometrial in situ steroid metabolism, which involves EST, overview	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	women from Chile	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
uterine endometrium	healthy and hyperplasic endometrium	Homo sapiens	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	activity in healthy and hyperplasic endometrium with or without polycystic ovary syndrome, overview	Homo sapiens

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3'-phosphoadenylyl sulfate + estrone	-	Homo sapiens	adenosine 3',5'-bisphosphate + estrone 3-sulfate	-	?
additional information	the endocrinological status of women bearing polycystic ovarian syndrome, PCOS, affects the endometrial in situ steroid metabolism, which involves EST, overview	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
EST	-	Homo sapiens
estrogen sulfotransferase	-	Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
37	-	assay at	Homo sapiens

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.4	-	assay at	Homo sapiens

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Release 2023.1 (January 2023)