Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.4 extracted from

  • Gonzalez, A.; Cos, S.; Martinez-Campa, C.; Alonso-Gonzalez, C.; Sanchez-Mateos, S.; Mediavilla, M.D.; Sanchez-Barcelo, E.J.
    Selective estrogen enzyme modulator actions of melatonin in human breast cancer cells (2008), J. Pineal Res., 45, 86-92.
    View publication on PubMed
Search for more literature for 2.8.2.4

Activating Compound

Activating Compound Comment Organism Structure
Melatonin the level of EST mRNA steady-state of cells treated with melatonin is three times higher than that in control cells Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
EST expression analysis in presence and absence of melatonin Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + estradiol Homo sapiens
-
 adenosine 3',5'-bisphosphate + estradiol sulfate
-
 ?
additional information Homo sapiens the enzyme responsible for the formation of the biologically inactive estrogen sulfates ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
breast cancer cell
-
 Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + estradiol
-
 Homo sapiens adenosine 3',5'-bisphosphate + estradiol sulfate
-
 ?
additional information the enzyme responsible for the formation of the biologically inactive estrogen sulfates Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
EST
-
 Homo sapiens
estrogen sulfotransferase
-
 Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
 assay at Homo sapiens