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Literature summary for 2.8.2.4 extracted from
- Expression of aromatase and estrogen sulfotransferase in preinvasive and invasive breast cancer (2008), J. Cancer Res. Clin. Oncol., 134, 67-73.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| EST expression and regulation in invasive breast cancer and ductal carcinoma in situ, overview | Homo sapiens |
| expression analysis of the enzyme in healthy and preinvasive and invasive tumor breast tissue | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + estradiol | Homo sapiens | EST expression and regulation in invasive breast cancer and ductal carcinoma in situ, overview | adenosine 3',5'-bisphosphate + estradiol 3-sulfate | - |
? |  |
| additional information | Homo sapiens | local regulation of estradiol and EST in ductal carcinoma, DCIS, correlation between aromatase and EST expression and grade of malignancy in ductal carcinoma, overview | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| breast | - |
Homo sapiens | - |
| breast cancer cell | preinvasive and invasive cancer cells | Homo sapiens | - |
| breast cancer cell | invasive, postmenopausal women | Homo sapiens | - |
| breast invasive ductal carcinoma cell | - |
Homo sapiens | - |
| epithelial cell | - |
Homo sapiens | - |
| epithelium | - |
Homo sapiens | - |
| additional information | expression analysis of the enzyme in healthy and preinvasive and invasive tumor breast tissue, no stromal expression | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + estradiol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + estradiol 3-sulfate | - |
? | |
| 3'-phosphoadenylyl sulfate + estradiol | EST expression and regulation in invasive breast cancer and ductal carcinoma in situ, overview | Homo sapiens | adenosine 3',5'-bisphosphate + estradiol 3-sulfate | - |
? | |
| additional information | local regulation of estradiol and EST in ductal carcinoma, DCIS, correlation between aromatase and EST expression and grade of malignancy in ductal carcinoma, overview | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| EST | - |
Homo sapiens |
| estrogen sulfotransferase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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