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Literature summary for 2.8.2.4 extracted from

  • van Lipzig, M.M.; Commandeur, J.N.; de Kanter, F.J.; Damsten, M.C.; Vermeulen, N.P.; Maat, E.; Groot, E.J.; Brouwer, A.; Kester, M.H.; Visser, T.J.; Meerman, J.H.
    Bioactivation of dibrominated biphenyls by cytochrome P450 activity to metabolites with estrogenic activity and estrogen sulfotransferase inhibition capacity (2005), Chem. Res. Toxicol., 18, 1691-1700.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
2-OH-3,2'-dibromobiphenyl
-
 Homo sapiens
3-OH-2,2'-dibromobiphenyl
-
 Homo sapiens
3-OH-4,4'-dibromobiphenyl
-
 Homo sapiens
4-OH-2,2'-dibromobiphenyl
-
 Homo sapiens
4-OH-3,4'-dibromobiphenyl
-
 Homo sapiens
4-OH-4'-monobromobiphenyl
-
 Homo sapiens
6-OH-2,2'-dibromobiphenyl
-
 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 recombinant enzyme expressed in Salmonella typhimurium
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
17beta-estradiol + 3'-phosphoadenylyl sulfate
-
 Homo sapiens adenosine 3',5'-bisphosphate + 17beta-estradiol 3-sulfate
-
 ?

Synonyms

Synonyms Comment Organism
estrogen sulfotransferase
-
 Homo sapiens
hEST
-
 Homo sapiens