Cloned (Comment) | Organism |
---|---|
EST cDNA subcloned into pKK233-2 and expressed in Escherichia coli XL1-Blue | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
quercetin | competitive inhibition | Homo sapiens | |
resveratrol | competitive inhibition | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00032 | - |
quercetin | pH 7.4, 37°C | Homo sapiens | |
0.00058 | - |
resveratrol | pH 7.4, 37°C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epithelium | mammary epithelial cells | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + 17beta-estradiol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + estradiol 3-sulfate | - |
r | |
3'-phosphoadenylylsulfate + quercetin | - |
Homo sapiens | adenosine 3',5'-bisphosphate + quercetin sulfate | - |
r | |
3'-phosphoadenylylsulfate + resveratrol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + resveratrol sulfate | - |
r |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00036 | - |
resveratrol | pH 7.4, 37°C | Homo sapiens | |
0.00058 | - |
quercetin | pH 7.4, 37°C | Homo sapiens |