Cloned (Comment) | Organism |
---|---|
isoform rEST-6 cloned and expressed in Escherichia coli | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
17beta-estradiol | substrate inhibition | Rattus norvegicus | |
estrone | substrate inhibition | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Rattus norvegicus | 5829 | - |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | varying the Mg2+ concentration from 0-10 mM in the beta-estradiol sulfation reaction does not affect the sulfation activity of isoform rEST-6 | Rattus norvegicus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
35300 | - |
calculated from putative amino acid sequence | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
rat | - |
Purification (Comment) | Organism |
---|---|
isoform rEST-6 | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + 17beta-estradiol | isoform rEST-6 | Rattus norvegicus | adenosine 3',5'-bisphosphate + estradiol 3-sulfate | - |
r | |
3'-phosphoadenylylsulfate + estrone | isoform rEST-6 | Rattus norvegicus | adenosine 3',5'-bisphosphate + estrone 3-sulfate | - |
r | |
additional information | isoform rEST-6 selectively expressed in male rats sulfates estrogens, but dehydroepiandrosterone, pregnenolone, cortisol or testosterone are no substrates | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EST | - |
Rattus norvegicus |
rEST-6 | - |
Rattus norvegicus |