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Literature summary for 2.8.2.33 extracted from
- Oversulfated chondroitin sulfate plays critical roles in the neuronal migration in the cerebral cortex (2008), J. Biol. Chem., 283, 32610-32620.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | - |
Mus musculus | 5794 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + chondroitin | Mus musculus | the enzyme plays a critical role in the biosynthesis of oversulfated structures | adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? |  |
| 3'-phosphoadenylyl sulfate + GlcAbeta1-3GalNAc(4-O-sulfate) | Mus musculus | GlcAbeta1-3GalNAc(4,6-O-disulfate) units are synthesized through sulfation of GlcAbeta1-3GalNAc(4-O-sulfate) units by the enzyme | adenosine 3',5'-bisphosphate + GlcAbeta1-3GalNAc(4,6-O-disulfate) | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| embryo | - |
Mus musculus | - |
| neocortex | of mouse embryo | Mus musculus | - |
| neuron | cortical neuron | Mus musculus | - |
| subventricular zone | - |
Mus musculus | - |
| ventricular zone | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + chondroitin | - |
Mus musculus | adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? | |
| 3'-phosphoadenylyl sulfate + chondroitin | the enzyme plays a critical role in the biosynthesis of oversulfated structures | Mus musculus | adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? | |
| 3'-phosphoadenylyl sulfate + GlcAbeta1-3GalNAc(4-O-sulfate) | GlcAbeta1-3GalNAc(4,6-O-disulfate) units are synthesized through sulfation of GlcAbeta1-3GalNAc(4-O-sulfate) units by the enzyme | Mus musculus | adenosine 3',5'-bisphosphate + GlcAbeta1-3GalNAc(4,6-O-disulfate) | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GalNAc4S-6ST | - |
Mus musculus |
| N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase | 4,6-ST | Mus musculus |
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Release 2023.1 (January 2023)
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