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Literature summary for 2.8.2.33 extracted from

  • Inoue, H.; Otsu, K.; Suzuki, S.; Nakanishi, Y.
    Difference between N-acetylgalactosamine 4-sulfate 6-O-sulfotransferases from human serum and squid cartilage in specificity toward the terminal and interior portion of chondroitin sulfate (1986), J. Biol. Chem., 261, 4470-4475.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
CaCl2 5 mM, 2.5 fold stimulation of interior sulfotransferase activity, 1.9 fold stimulation of terminal sulfotransferase activity Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0038
-
UDP-GalNAc 4-sulfate pH 5.2 Homo sapiens
0.027
-
chondroitin 4-sulfate pH 6.9 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.0022
-
substrate UDP-GalNAc 4-sulfate, pH 5.2 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin 4-sulfate
-
Homo sapiens adenosine 3',5'-bisphosphate + chondroitin 4,6'-disulfate major terminal sulfotransferase activity plus a minor interior sulfotransferase activity ?
3'-phosphoadenylyl sulfate + chondroitin 4-sulfate
-
Homo sapiens adenosine 3',5'-bisphosphate + chondroitin sulfate E
-
?
3'-phosphoadenylyl sulfate + dermatan sulfate source pig skin Homo sapiens adenosine 3',5'-bisphosphate + dermatan sulfate 6'-sulfate
-
?
3'-phosphoadenylyl sulfate + glucuronic acid-GalNAc(SO4)-glucuronic acid-GalNAc(SO4)
-
Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?
3'-phosphoadenylyl sulfate + UDP-GalNAc 4-sulfate
-
Homo sapiens adenosine 3',5'-bisphosphate + UDP-GalNAc-4,6-disulfate
-
?