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Literature summary for 2.8.2.30 extracted from

  • Liu, J.; Shriver, Z.; Blaiklock, P.; Yoshida, K.; Sasisekharan, R.; Rosenberg, R.D.
    Heparan sulfate D-glucosaminyl 3-O-sulfotransferase-3A sulfates N-unsubstituted glucosamine residues (1999), J. Biol. Chem., 274, 38155-38162.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Sf9 cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
39000
-
x * 39000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine Homo sapiens isoform 3A modifies two novel tetrasaccharides of 3-O-sulfated heparan sulfate: deltaUA2S-GlcNS-IdoUA2S-S-GlcNH23S and deltaUA2S-GlcNS-IdoUA2S-3S-GlcNH23S6S adenosine 3',5'-diphosphate + [heparan sulfate]-glucosamine 3-sulfate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
to homogeneity, recombinant isoform 3A Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + chondroitin sulfate A isoform 3A, low activity Homo sapiens adenosine 3',5'-diphosphate + ?
-
?
3'-phosphoadenylyl sulfate + keratan sulfate isoform 3A, low activity Homo sapiens adenosine 3',5'-diphosphate + ?
-
?
3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine isoform 3A modifies two novel tetrasaccharides of 3-O-sulfated heparan sulfate: deltaUA2S-GlcNS-IdoUA2S-S-GlcNH23S and deltaUA2S-GlcNS-IdoUA2S-3S-GlcNH23S6S Homo sapiens adenosine 3',5'-diphosphate + [heparan sulfate]-glucosamine 3-sulfate
-
?

Subunits

Subunits Comment Organism
? x * 39000, SDS-PAGE Homo sapiens