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Literature summary for 2.8.2.23 extracted from
- Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice (2008), J. Comp. Neurol., 511, 543-556.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | usefulness of HS3ST-2 as a genetic marker for TrkC-positive mechanosensory neurons | Mus musculus |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| HS3ST-2 gene, expression in neurons, expression analysis in vivo, overview | Mus musculus |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | generation of a HS3ST-2-hPLAP knock-in mouse line, in which HS3ST-2-expressing neurons and their projections are labeled by human placental alkaline phosphatase, hPLAP, analysis fo the morphological subtypes of HS3ST-2/TrkC-expressing neurons, phenotype: in the glabrous and hairy skin, rare Merkel endings and transverse lanceolate endings are weakly stained, subcellular localization of the isozyme HS3ST-2, overview | Mus musculus |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | subcellular localization of HS3ST-2 in neurons, overview | Mus musculus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Mus musculus | HS3ST-2 is a marker for specific subsets of TrkC-expressing cutaneous low-threshold mechanosensory and proprioceptive mechanosensory neurons, overview. HS3ST-2 is involved in formation of sensory endings of nerves in skeletal muscle | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
HS3ST-2 gene | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| neuron | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | HS3ST-2 is a marker for specific subsets of TrkC-expressing cutaneous low-threshold mechanosensory and proprioceptive mechanosensory neurons, overview. HS3ST-2 is involved in formation of sensory endings of nerves in skeletal muscle | Mus musculus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| heparan sulfate D-glucosaminyl 3-O-sulfotransferase 2 | - |
Mus musculus |
| HS3ST-2 | - |
Mus musculus |
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Release 2023.1 (January 2023)
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