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Literature summary for 2.8.2.21 extracted from

  • Torii, T.; Fukuta, M.; Habuchi, O.
    Sulfation of sialyl N-acetyllactosamine oligosaccharides and fetuin oligosaccharides by keratan sulfate Gal-6-sulfotransferase (2000), Glycobiology, 10, 203-211.
    View publication on PubMed
Search for more literature for 2.8.2.21

Activating Compound

Activating Compound Comment Organism Structure
protamine weak activator, less efficient than Ca2+ Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00058
-
 3'-phosphoadenylylsulfate pH 6.4, 37°C Homo sapiens
0.38
-
 Keratan sulfate pH 6.4, 37°C Homo sapiens

Metals/Ions

Metals/Ions Comment Organism Structure
Ba2+ activates Homo sapiens
Ca2+ highest stimulatory activity, optimum concentration at 10 mM Homo sapiens
Mg2+ activates Homo sapiens
Mn2+ highest stimulatory activity Homo sapiens
Sr2+ activates Homo sapiens
Zn2+ activates Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + fetuin
-
 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + keratan sulfate
-
 Homo sapiens adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
 ?
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1(6-sulfo)GlcNAcbeta1-3(6-sulfo)Galbeta1-4(6-sulfo)GlcNAc sulfation at position 6 of Gal residues Homo sapiens adenosine 3',5'-bisphosphate + NeuAcalpha2-3-(6-sulfo)Galbeta1-(6-sulfo)GlcNAcbeta1-3(6-sulfo)Galbeta1-4(6-sulfo)GlcNAc
-
 ?
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1-4GlcNAc sulfation at position 6 of Gal residues, no sulfation of GlcNAc Homo sapiens adenosine 3',5'-bisphosphate + NeuAcalpha2-3(6-sulfo)Galbeta1-4GlcNAc
-
 ?
3'-phosphoadenylylsulfate + NeuAcalpha2-3Galbeta1-4GlcNAcbeta1-3Galbeta1-4GlcNAc sulfation at position 6 of Gal residues Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Homo sapiens