Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.21 extracted from

  • Akama, T.O.; Nakayama, J.; Nishida, K.; Hiraoka, N.; Suzuki, M.; McAuliffe, J.; Hindsgaul, O.; Fukuda, M.; Fukuda, M.N.
    Human corneal GlcNac 6-O-sulfotransferase and mouse intestinal GlcNac 6-O-sulfotransferase both produce keratan sulfate (2001), J. Biol. Chem., 276, 16271-16278.
    View publication on PubMed
Search for more literature for 2.8.2.21

Cloned(Commentary)

Cloned (Comment) Organism
corneal enzyme Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens Gn6ST produces keratan sulfate in cooperation with KSG6ST, inactivation of Gn6ST may lead to macular corneal dystrophy ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cornea
-
 Mus musculus
-
cornea
-
 Homo sapiens
-
intestine
-
 Mus musculus
-
intestine
-
 Homo sapiens
-
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + GlcNAcbeta1-3Galbeta1-4GlcNACbeta1-3Galbeta1-4GlcNAcbeta1-6Manalpha1-6Manbeta-octyl synthetic substrate, sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?
3'-phosphoadenylylsulfate + keratan sulfate sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase Mus musculus adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
 ?
3'-phosphoadenylylsulfate + keratan sulfate sulfation at position 6 of N-acetylgalactosamine residues, GlcNAc 6-O-sulfotransferase Homo sapiens adenosine 3',5'-bisphosphate + keratan 6'-sulfate
-
 ?
additional information Gn6ST produces keratan sulfate in cooperation with KSG6ST, inactivation of Gn6ST may lead to macular corneal dystrophy Homo sapiens ?
-
 ?