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Literature summary for 2.8.2.20 extracted from

  • Hartmann-Fatu, C.; Bayer, P.
    Determinants of tyrosylprotein sulfation coding and substrate specificity of tyrosylprotein sulfotransferases in metazoans (2016), Chem. Biol. Interact., 259, 17-22.
    View publication on PubMed
Search for more literature for 2.8.2.20

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi apparatus
-
 Homo sapiens 5794
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylyl sulfate + protein tyrosine Homo sapiens
-
 adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O60507
-
-
Homo sapiens O60704
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HUVEC cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + protein tyrosine
-
 Homo sapiens adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
TPST
-
 Homo sapiens
TPST-1 isoform Homo sapiens
TPST-2 isoform Homo sapiens
tyrosylprotein sulfotransferase
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens isoform TPST-1 is down-regulated in a dose-dependent manner when increasing shear stress stimulus is applied to cells down
Homo sapiens isoform TPST-2 is up-regulated in a dose-dependent manner when increasing shear stress stimulus is applied to cells up