Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.8.2.20 extracted from

  • Seibert, C.; Cadene, M.; Sanfiz, A.; Chait, B.T.; Sakmar, T.P.
    Tyrosine sulfation of CCR5 N-terminal peptide by tyrosylprotein sulfotransferases 1 and 2 follows a discrete pattern and temporal sequence (2002), Proc. Natl. Acad. Sci. USA, 99, 11031-11036.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
2 isoforms: TPST1 and TPST2 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
2 isoforms: TPST1 and TPST2
-

Purification (Commentary)

Purification (Comment) Organism
2 recombinant isoforms: TPST1 and TPST2 Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + DYQVSSPIYDINYYTSE amino acids 2-18 derived from peptide CC-chemokine receptor 5, final product has four sulfotyrosine residues, sulfation occurs in the following order: Tyr13, Tyr14, Tyr9, Tyr2 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?
3'-phosphoadenylylsulfate + QATEYEYLDYDFLPE derived from N-terminal residues of the mature leukocyte adhesion molecule P-selectin glycoprotein ligand 1 Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?