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Literature summary for 2.8.2.20 extracted from

  • Kasinathan, C.; Rizwan, M.; Slomiany, A.; Slomiany, B.L.
    Effect of sofalcone on tyrosylprotein sulfotransferase (1994), Gen. Pharmacol., 25, 1017-1020.
    View publication on PubMed
Search for more literature for 2.8.2.20

Activating Compound

Activating Compound Comment Organism Structure
5'-AMP optimal concentration 2 mM Rattus norvegicus
dithiothreitol 1 mM Rattus norvegicus
Nonidet P-40 6fold stimulation at 0.5% Rattus norvegicus
sodium dodecylsulfate 2fold stimulation at 0.1% Rattus norvegicus
Sofalcone 55% stimulation Rattus norvegicus
Triton X-100 6fold stimulation at 0.5% Rattus norvegicus
Tween 20 6fold stimulation at 0.5% Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
EDTA 10 mM Rattus norvegicus
N-ethylmaleimide 1 mM Rattus norvegicus
NaCl above 100 mM, gastric enzyme Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
Golgi membrane
-
 Rattus norvegicus 139
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ activation by 10 mM divalent cations in decreasing order of efficiency: Mn2+, Ca2+, Cu2+, Mg2+, Zn2+ Rattus norvegicus
Cu2+ activation by 10 mM divalent cations in decreasing order of efficiency: Mn2+, Ca2+, Cu2+, Mg2+, Zn2+ Rattus norvegicus
Mg2+ activation by 10 mM divalent cations in decreasing order of efficiency: Mn2+, Ca2+, Cu2+, Mg2+, Zn2+ Rattus norvegicus
Mn2+ activation by 10 mM divalent cations in decreasing order of efficiency: Mn2+, Ca2+, Cu2+, Mg2+, Zn2+ Rattus norvegicus
Zn2+ activation by 10 mM divalent cations in decreasing order of efficiency: Mn2+, Ca2+, Cu2+, Mg2+, Zn2+ Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Sprague-Dawley
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + acidic amino acid polymer EAY i.e. poly-EAY or Glu6,Ala3,Tyr1, model substrate Rattus norvegicus adenosine 3',5'-bisphosphate + ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
-
 Rattus norvegicus