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Literature summary for 2.8.2.20 extracted from

  • Lin, W.H.; Roth, J.A.
    Characterization of a tyrosylprotein sulfotransferase in human liver (1990), Biochem. Pharmacol., 40, 629-635.
    View publication on PubMed
Search for more literature for 2.8.2.20

Activating Compound

Activating Compound Comment Organism Structure
Lubrol Px activation Homo sapiens
Triton X-100 activation Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
Poly-EAY substrate inhibition, above 0.002 mM Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0015 0.0016 peptide EAY
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Homo sapiens
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mn2+ requirement Homo sapiens
Mn2+ 30 mM Homo sapiens
additional information no requirement for Co2+ Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + peptide EAY
-
 Homo sapiens adenosine 3',5'-bisphosphate + peptide EAY(O-sulfate)
-
 ?
3'-phosphoadenylylsulfate + acidic amino acid polymer EAY i.e. poly-EAY or Glu6,Ala3,Tyr1, model substrate Homo sapiens adenosine 3',5'-bisphosphate + ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4
-
-
 Homo sapiens