Cloned (Comment) | Organism |
---|---|
gene SULT1A1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, SULT1A1 and SULT1A3 form a gene cluster with SULT1A1-like and SULT1A-like genes on chromosome 20, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis | Macaca fascicularis |
gene SULT1A1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, SULT1B1 and SULT1E1 form a gene cluster, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis | Macaca fascicularis |
gene SULT1A1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, SULT1B1 and SULT1E1 formed a gene cluster, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis | Macaca fascicularis |
gene SULT1A1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, SULT1C2v1, SULT1C2v2, and SULT1C4 form a gene cluster with a SULT1C3-like gene, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis | Macaca fascicularis |
gene SULT1A1, DNA and amino acid sequence determination and analysis, sequence comparisons and phylogenetic analysis, gene structure and genomic organization of each cynomolgus SULTs, SULT2A1 is located on chromosome 19 where also a SULT2B1-like gene is located, recombinant expression in Escherichia coli cytosol, quantitative real-time RT-PCR enzyme expression analysis | Macaca fascicularis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Macaca fascicularis | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + 1-naphthol | Macaca fascicularis | - |
adenosine 3',5'-bisphosphate + 1-naphthyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | Macaca fascicularis | - |
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dopamine | Macaca fascicularis | - |
adenosine 3',5'-bisphosphate + dopamine sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Macaca fascicularis | - |
- |
- |
Macaca fascicularis | A0A2K5UIK9 | - |
- |
Macaca fascicularis | A0A2K5VZW5 | - |
- |
Macaca fascicularis | A0A2K5X3B6 | - |
- |
Macaca fascicularis | P52842 | - |
- |
Macaca fascicularis | Q2XV97 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Macaca fascicularis | - |
brain | - |
Macaca fascicularis | - |
brain | very low level | Macaca fascicularis | - |
heart | - |
Macaca fascicularis | - |
heart | low level | Macaca fascicularis | - |
jejunum | predominantly | Macaca fascicularis | - |
jejunum | very low level | Macaca fascicularis | - |
jejunum | high level | Macaca fascicularis | - |
jejunum | moderate level | Macaca fascicularis | - |
kidney | - |
Macaca fascicularis | - |
kidney | predominantly | Macaca fascicularis | - |
kidney | high level | Macaca fascicularis | - |
liver | - |
Macaca fascicularis | - |
liver | predominantly | Macaca fascicularis | - |
liver | predominately | Macaca fascicularis | - |
lung | - |
Macaca fascicularis | - |
additional information | quantitative real-time RT-PCR enzyme expression analysis in female and male tissue samples, tissue distribution and expression pattern, overview | Macaca fascicularis | - |
additional information | quantitative real-time RT-PCR enzyme expression analysis in female and male tissue samples, tissue distribution and expression pattern, overview. SULT1A3 is expressed in all the tissues, but most predominantly in jejunum, followed by liver | Macaca fascicularis | - |
ovary | - |
Macaca fascicularis | - |
small intestine | - |
Macaca fascicularis | - |
testis | - |
Macaca fascicularis | - |
testis | low level | Macaca fascicularis | - |
testis | moderate to low level | Macaca fascicularis | - |
uterus | - |
Macaca fascicularis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + 1-naphthol | - |
Macaca fascicularis | adenosine 3',5'-bisphosphate + 1-naphthyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 1-naphthol | best substrate | Macaca fascicularis | adenosine 3',5'-bisphosphate + 1-naphthyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 1-naphthol | high activity | Macaca fascicularis | adenosine 3',5'-bisphosphate + 1-naphthyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 17beta-estradiol | - |
Macaca fascicularis | adenosine 3',5'-bisphosphate + 17beta-estradiol sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 17beta-estradiol | best substrate | Macaca fascicularis | adenosine 3',5'-bisphosphate + 17beta-estradiol sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 4-nitrophenol | - |
Macaca fascicularis | adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + 4-nitrophenol | best substrate | Macaca fascicularis | adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | - |
Macaca fascicularis | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dehydroepiandrosterone | best substrate | Macaca fascicularis | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
3'-phosphoadenylyl sulfate + dopamine | - |
Macaca fascicularis | adenosine 3',5'-bisphosphate + dopamine sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cytosolic sulfotransferase | - |
Macaca fascicularis |
More | cf. EC 2.8.2.4 | Macaca fascicularis |
SULT1A3 | - |
Macaca fascicularis |
SULT1B1 | - |
Macaca fascicularis |
SULT1C2 | - |
Macaca fascicularis |
SULT1C2v1 | - |
Macaca fascicularis |
SULT1C2v2 | - |
Macaca fascicularis |
SULT1C4 | - |
Macaca fascicularis |
SULT2A1 | - |
Macaca fascicularis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Macaca fascicularis |
General Information | Comment | Organism |
---|---|---|
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. SULT1A3 and SULT1A4 have arisen from the single gene by gene duplication and encode the same protein. Tissue distribution and sbstrate specificities of SULTS from humans and Cynomolgus macaques, overview | Macaca fascicularis |
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. SULT1B1 and SULT1E1 form a gene cluster | Macaca fascicularis |
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. SULT1B1 and SULT1E1 formed a gene cluster. Tissue distribution and sbstrate specificities of SULTS from humans and Cynomolgus macaques, overview | Macaca fascicularis |
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. SULT1C2v1, SULT1C2v2, and SULT1C4 form a gene cluster with a SULT1C3-like gene. Tissue distribution and sbstrate specificities of SULTS from humans and Cynomolgus macaques, overview | Macaca fascicularis |
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. The cynomolgus SULT1C2v2 is highly homologous to human SULT1C2P1 (pseudogene). Tissue distribution and sbstrate specificities of SULTS from humans and Cynomolgus macaques, overview | Macaca fascicularis |
evolution | gene structure and genomic organization of each cynomolgus SULTs are similar to those of the human orthologues. Tissue distribution and sbstrate specificities of SULTS from humans and Cynomolgus macaques, overview | Macaca fascicularis |