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Literature summary for 2.8.2.2 extracted from
- Pentachlorophenol and other chlorinated phenols are substrates for human hydroxysteroid sulfotransferase hSULT2A1 (2008), Chem. Res. Toxicol., 21, 1503-1508.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| SULT2A1, expression in Escherichia coli | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + dehydroepiandrosterone | Homo sapiens | - |
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant SULT2A1 from Escherichia coli by anion exchange chromatography, ultrafiltration, and hydroxyapatite chromatography | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + dehydroepiandrosterone | - |
Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
? | |
| additional information | pentachlorophenols, tetrachlorophenols, and trichlorophenols are substrates of isozyme SULT2A1, while mono- and dichlorophenol are poor substrates, cf. EC 2.8.2.15 | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hydroxysteroid sulfotransferase | - |
Homo sapiens |
| More | cf. EC 2.8.2.15 | Homo sapiens |
| SULT2A1 | - |
Homo sapiens |
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