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Literature summary for 2.8.2.2 extracted from

  • Narasaka, T.; Moriya, T.; Endoh, M.; Suzuki, T.; Shizawa, S.; Mizokami, Y.; Matsuoka, T.; Sasano, H.
    17Beta-hydroxysteroid dehydrogenase type 2 and dehydroepiandrosterone sulfotransferase in the human liver (2000), Endocr. J., 47, 697-705.
    View publication on PubMed

Application

Application Comment Organism
medicine diagnostic of liver diseases, in chronic hepatitis the immunopositive area of DHEA-ST is significantly increased compared to normal liver Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + dehydroepiandrosterone Homo sapiens
-
adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
r

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
human
-

Source Tissue

Source Tissue Comment Organism Textmining
fetus
-
Homo sapiens
-
hepatocyte
-
Homo sapiens
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylylsulfate + dehydroepiandrosterone
-
Homo sapiens adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate
-
r
additional information hepatic clearance and metabolism of sex steroids Homo sapiens ?
-
?