Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NaCl | leads to a greater activation of the cDNA-expressed DHEA ST when assayed with dehydroepiandrosterone | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
DHEA ST cloned from cDNA and expressed in COS-1 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2,6-Dichloro-4-nitrophenol | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00013 | - |
3'-phosphoadenylylsulfate | pH 7.5, 37°C | Homo sapiens | |
3.9 | - |
minoxidil | pH 7.5, 37°C | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + dehydroepiandrosterone | Homo sapiens | biotransformation of xenobiotics and hormones through sulfate conjugation, important metabolic pathway | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
human | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + dehydroepiandrosterone | - |
Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
r | |
3'-phosphoadenylylsulfate + dehydroepiandrosterone | biotransformation of xenobiotics and hormones through sulfate conjugation, important metabolic pathway | Homo sapiens | adenosine 3',5'-bisphosphate + dehydroepiandrosterone 3-sulfate | - |
r | |
3'-phosphoadenylylsulfate + minoxidil | antihypertensive agent and hair growth stimulator, activation by sulfation | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
DHEA ST | - |
Homo sapiens |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
4 | 43 | 50% inactivation temperature for COS-expressed enzyme 42°C | Homo sapiens |