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Literature summary for 2.8.2.18 extracted from
- Enzymatic sulfation of steroids. XIV. The glucocorticoid sulfotransferases of Bos Taurus liver (1981), Comp. Biochem. Physiol. B, 69, 511-516.
No PubMed abstract available
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
| cytosol | - |
Bos taurus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 45700 | - |
gel filtration, 2 enzyme species: 62100 Da and 45700 Da | Bos taurus |
| 62100 | - |
gel filtration, 2 enzyme species: 62100 Da and 45700 Da | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylylsulfate + cortisol | Rattus norvegicus | - |
adenosine 3',5'-bisphosphate + cortisol 21-sulfate | - |
? |  |
| 3'-phosphoadenylylsulfate + cortisol | Bos taurus | - |
adenosine 3',5'-bisphosphate + cortisol 21-sulfate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Rattus norvegicus | - |
female Sprague-Dawley CD rats | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial, 2 sulfotransferases: I and II | Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylylsulfate + cortisol | - |
Rattus norvegicus | adenosine 3',5'-bisphosphate + cortisol 21-sulfate | - |
? | |
| 3'-phosphoadenylylsulfate + cortisol | - |
Bos taurus | adenosine 3',5'-bisphosphate + cortisol 21-sulfate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | - |
sulfotransferase I | Bos taurus |
| 7.4 | - |
sulfotransferase II | Bos taurus |
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Release 2023.1 (January 2023)
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