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Literature summary for 2.8.2.17 extracted from
- Chondroitin 6-sulfation regulates perineuronal net formation by controlling the stability of aggrecan (2016), Neural Plast., 2016, 1305801.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + chondroitin | Mus musculus | - |
adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | O88199 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylyl sulfate + chondroitin | - |
Mus musculus | adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| C6ST-1 | - |
Mus musculus |
| chondroitin 6-sulfotransferase-1 | - |
Mus musculus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | overexpression of chondroitin 6-sulfotransferase-1 selectively decreases aggrecan, a major chondroitin sulfate proteoglycans in perineuronal nets, in the aged brain without affecting other perineuronal net components | Mus musculus |
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Release 2023.1 (January 2023)
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