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Literature summary for 2.8.2.17 extracted from
- Enzymatic sulfation of galactose residue of keratan sulfate by chondroitin 6-sulfotransferase (1996), Glycobiology, 6, 51-57.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| protamine | - |
Gallus gallus |  |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
- |
Gallus gallus |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0007 | - |
3'-phosphoadenylylsulfate | pH 6.8, 37°C | Gallus gallus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
| Ca2+ | stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
| Co2+ | good activator, stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
| Cu2+ | stimulates chondroitin 6-sulfotransferase activity but not keratan sulfate sulfotransferase activity | Gallus gallus | |
| Mg2+ | stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
| Mn2+ | stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
| Sr2+ | stimulates chondroitin 6-sulfotransferase activity and keratan sulfate sulfotransferase activity | Gallus gallus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Gallus gallus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cornea | - |
Gallus gallus | - |
| epiphysis | cartilage, embryo | Gallus gallus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 3'-phosphoadenylylsulfate + chondroitin | - |
Gallus gallus | adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate | - |
? | |
| 3'-phosphoadenylylsulfate + corneal keratan sulfate | - |
Gallus gallus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.8 | - |
chondroitin 6-sulfotransferase activity | Gallus gallus |
| 6.2 | - |
keratan sulfate sulfotransferase activity | Gallus gallus |
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