Application | Comment | Organism |
---|---|---|
medicine | concomitant ingestion of beverages such as green tea and black tea may increase the bioavailability of orally administered ritodrine, and perhaps other beta-agonists | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli, enzyme form SULT1A3 | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | enzyme form SULT1A1 is significantly inhibited by all beverages examined (grapefruit juice, orange juice, green tea and black tea) at a concentration of 10%. Green tea and black tea exhibit potent inhibition, even at a concentration of 5%, they both inhibit SULT1A1 by 100%; enzyme form SULT1A3 is significantly inhibited by all beverages examined (grapefruit juice, orange juice, green tea and black tea) at a concentration of 10%. Green tea and black tea exhibit potent inhibition, even at a concentration of 5%, they both inhibit SULT1A3 by more than 95% | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.438 | - |
ritodrine | enzyme form SULT1A3 | Homo sapiens | |
3.08 | - |
ritodrine | enzyme form SULT1A1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
enzyme form SULT1A1 | - |
Homo sapiens | - |
enzyme form SULT1A3 | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme, enzyme form SULT1A3 | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestinal mucosa | enzyme form SULT1A1 | Homo sapiens | - |
intestinal mucosa | enzyme form SULT1A3 | Homo sapiens | - |
liver | enzyme form SULT1A1 | Homo sapiens | - |
liver | enzyme form SULT1A3 | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + ritodrine | enzyme form SULT1A1 | Homo sapiens | adenosine 3',5'-bisphosphate + ritodrine sulfate | - |
? | |
3'-phosphoadenylylsulfate + ritodrine | enzyme form SULT1A3 | Homo sapiens | adenosine 3',5'-bisphosphate + ritodrine sulfate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SULT1A1 | - |
Homo sapiens |
SULT1A3 | - |
Homo sapiens |