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Literature summary for 2.8.2.1 extracted from

  • Yeh, C.T.; Yen, G.C.
    Effects of phenolic acids on human phenolsulfotransferases in relation to their antioxidant activity (2003), J. Agric. Food Chem., 51, 1474-1479.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
ferulic acid activation of M-PST Homo sapiens
gallic acid activation of P-PST and M-PST Homo sapiens
gentisic acid activation of P-PST and M-PST Homo sapiens
m-coumaric acid activation of P-PST Homo sapiens
o-coumaric acid activation of P-PST Homo sapiens
p-coumaric acid activation of P-PST Homo sapiens
p-hydroxybenzoic acid activation of P-PST and M-PST Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
caffeic acid inhibition of P-PST and M-PST Homo sapiens
chlorogenic acid inhibition of P-PST and M-PST Homo sapiens
protocatechuic acid inhibition of P-PST and M-PST Homo sapiens
Sinapic acid inhibition of P-PST and M-PST Homo sapiens
syringic acid inhibition of P-PST and M-PST Homo sapiens
vanillic acid inhibition of P-PST and M-PST Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3'-phosphoadenylylsulfate + a phenol Homo sapiens sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds adenosine 3',5'-bisphosphate + an aryl sulfate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST
-

Source Tissue

Source Tissue Comment Organism Textmining
platelet M-PST Homo sapiens
-
platelet P-PST Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3'-phosphoadenylyl sulfate + a phenol
-
Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
?
3'-phosphoadenylylsulfate + 4-nitrophenol P-PST Homo sapiens adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate
-
?
3'-phosphoadenylylsulfate + a phenol sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds Homo sapiens adenosine 3',5'-bisphosphate + an aryl sulfate
-
?
3'-phosphoadenylylsulfate + dopamine M-PST Homo sapiens adenosine 3',5'-bisphosphate + ?
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7
-
assay at Homo sapiens