Activating Compound | Comment | Organism | Structure |
---|---|---|---|
ferulic acid | activation of M-PST | Homo sapiens | |
gallic acid | activation of P-PST and M-PST | Homo sapiens | |
gentisic acid | activation of P-PST and M-PST | Homo sapiens | |
m-coumaric acid | activation of P-PST | Homo sapiens | |
o-coumaric acid | activation of P-PST | Homo sapiens | |
p-coumaric acid | activation of P-PST | Homo sapiens | |
p-hydroxybenzoic acid | activation of P-PST and M-PST | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
caffeic acid | inhibition of P-PST and M-PST | Homo sapiens | |
chlorogenic acid | inhibition of P-PST and M-PST | Homo sapiens | |
protocatechuic acid | inhibition of P-PST and M-PST | Homo sapiens | |
Sinapic acid | inhibition of P-PST and M-PST | Homo sapiens | |
syringic acid | inhibition of P-PST and M-PST | Homo sapiens | |
vanillic acid | inhibition of P-PST and M-PST | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylylsulfate + a phenol | Homo sapiens | sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
2 forms: simple phenol sulfating P-PST, monoamine sulfating M-PST | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
platelet | M-PST | Homo sapiens | - |
platelet | P-PST | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3'-phosphoadenylyl sulfate + a phenol | - |
Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
3'-phosphoadenylylsulfate + 4-nitrophenol | P-PST | Homo sapiens | adenosine 3',5'-bisphosphate + 4-nitrophenyl sulfate | - |
? | |
3'-phosphoadenylylsulfate + a phenol | sulfate conjugation of phenolic biogenic amines, important in the biotransformation of many neurotransmitters, hormones, drugs, and xenobiotic compounds | Homo sapiens | adenosine 3',5'-bisphosphate + an aryl sulfate | - |
? | |
3'-phosphoadenylylsulfate + dopamine | M-PST | Homo sapiens | adenosine 3',5'-bisphosphate + ? | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
assay at | Homo sapiens |