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Literature summary for 2.8.1.B3 extracted from

  • Wright, C.M.; Palenchar, P.M.
    Mueller, E.G.: A paradigm for biological sulfur transfers via persulfide groups: a persulfide-disulfide-thiol cycle in 4-thiouridine biosynthesis. (2002), Chem. Commun. (Camb. ), 2002, 2708-2709.
    View publication on PubMed
Search for more literature for 2.8.1.B3

Protein Variants

Protein Variants Comment Organism
C456A mutation impairs this sulfurtransferase activity. ThiI is incapable of supporting generation of 4-thiouridine in tRNA both in vitro and in vivo Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) Escherichia coli
-
 sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme also catalyzes the transfer of sulfur from thiosulfate to cyanide (EC 2.8.1.1) Escherichia coli ?
-
 ?
sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8)
-
 Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP
-
 ?
sulfurtransferase IscS-SSH + adenylated-tRNA-uridine(position8) ThiI receives the sulfur transferred from the persulfide group of the sulfurtransferase IscS. Formation of a disulfide bond between Cys-344 and Cys-456 of ThiI. Evidence for the persulfide–disulfide–thiol cycle at Cys-456 of ThiI Escherichia coli sulfurtransferase IscS-SH + tRNA-4-thiouridine(position8) + AMP
-
 ?

Synonyms

Synonyms Comment Organism
ThiI
-
 Escherichia coli