Literature summary for 2.8.1.8 extracted from

Cicchillo, R.M.; Booker, S.J.
Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide (2005), J. Am. Chem. Soc., 127, 2860-2861.

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Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
protein N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine	both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide	Escherichia coli	protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl radicals	-	?

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Release 2023.1 (January 2023)