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Literature summary for 2.8.1.7 extracted from
- Hydrogen sulfide is a novel potential virulence factor of Mycoplasma pneumoniae: characterization of the unusual cysteine desulfurase/desulfhydrase HapE (2016), Mol. Microbiol., 100, 42-54.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-cysteine + acceptor | Mycoplasma pneumoniae | - |
L-alanine + S-sulfanyl-acceptor | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mycoplasma pneumoniae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-cysteine + acceptor | - |
Mycoplasma pneumoniae | L-alanine + S-sulfanyl-acceptor | - |
? | |
| additional information | HapE is a bifunctional enzyme which has both the cysteine desulfurase activity to produce alanine and the cysteine desulfhydrase activity to produce pyruvate and hydrogen sulfide | Mycoplasma pneumoniae | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| hAPE | - |
Mycoplasma pneumoniae |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | the enzyme is a potential virulence factor of Mycoplasma pneumoniae being responsible for haemolysis | Mycoplasma pneumoniae |
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