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Literature summary for 2.8.1.7 extracted from

  • Adam, A.C.; Bornhövd, C.; Prokisch, H.; Neupert, W.; Hell, K.
    the Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria (2006), EMBO J., 25, 174-183.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
protein Isd11 forms a stable complex with Nfs1, prone to aggregation in the absence of Isd11 Saccharomyces cerevisiae

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrial matrix
-
Saccharomyces cerevisiae 5759
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
45000
-
x * 45000, SDS-PAGE, high-molecular-weight complex of Nfs1 and Isd11, gel filtration Saccharomyces cerevisiae
180000 200000 gel filtration Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
YPH499as WT, GAL10-ISD11 as Isd11-depleted strain
-
Saccharomyces cerevisiae Isd11-depleted
-
YPH499as WT, GAL10-ISD11 as Isd11-depleted strain
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification after lysis of mitochondria with detergents Saccharomyces cerevisiae

Purification (Commentary)

Purification (Comment) Organism
-
Saccharomyces cerevisiae

Subunits

Subunits Comment Organism
polymer x * 45000, SDS-PAGE, high-molecular-weight complex of Nfs1 and Isd11, gel filtration Saccharomyces cerevisiae

Synonyms

Synonyms Comment Organism
Nfs1
-
Saccharomyces cerevisiae