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Literature summary for 2.7.9.3 extracted from

  • McAllister, K.N.; Bouillaut, L.; Kahn, J.N.; Self, W.T.; Sorg, J.A.
    Using CRISPR-Cas9-mediated genome editing to generate C. difficile mutants defective in selenoproteins synthesis (2017), Sci. Rep., 7, 14672 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.9.3

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + selenide + H2O Clostridioides difficile
-
 AMP + selenophosphate + phosphate
-
 ?
ATP + selenide + H2O Clostridioides difficile R20291
-
 AMP + selenophosphate + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridioides difficile
-
-
-
Clostridioides difficile R20291
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + selenide + H2O
-
 Clostridioides difficile AMP + selenophosphate + phosphate
-
 ?
ATP + selenide + H2O
-
 Clostridioides difficile R20291 AMP + selenophosphate + phosphate
-
 ?

Synonyms

Synonyms Comment Organism
SelD
-
 Clostridioides difficile
selenophosphate synthetase
-
 Clostridioides difficile

General Information

General Information Comment Organism
malfunction the selD CRISPR deletion mutant has a growth defect in protein-rich medium and mimicks the phenotype of a generated TargeTron selD mutation Clostridioides difficile
physiological function the enzyme is essential for the specific incorporation of selenium into selenoproteins Clostridioides difficile