Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
glycosome | matrix | Trypanosoma cruzi | 20015 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
AMP + phosphoenolpyruvate + diphosphate | Trypanosoma cruzi | the enzyme likely works in the direction of pyruvate production. PPDK is a central enzyme in the metabolism of glycosome by providing a link between glycolysis fatty acid oxidation and biosynthetic diphosphate-producing pathways. PPDK seems to replace diphosphatase in its classical thermodynamic role of displacing the equilibrium of diphosphate-producing reactions, as well as in its role of eliminating the toxic diphosphate | ATP + pyruvate + phosphate | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma cruzi | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
epimastigote | - |
Trypanosoma cruzi | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
AMP + phosphoenolpyruvate + diphosphate | the enzyme likely works in the direction of pyruvate production. PPDK is a central enzyme in the metabolism of glycosome by providing a link between glycolysis fatty acid oxidation and biosynthetic diphosphate-producing pathways. PPDK seems to replace diphosphatase in its classical thermodynamic role of displacing the equilibrium of diphosphate-producing reactions, as well as in its role of eliminating the toxic diphosphate | Trypanosoma cruzi | ATP + pyruvate + phosphate | - |
r |
Synonyms | Comment | Organism |
---|---|---|
PPDK | - |
Trypanosoma cruzi |